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青岛地区缺血性脑血管病颅外颈动脉粥样硬化的调查
The Distribution of Arteriosclerosis of Extracranial Arteries Carotis in the Patients with Ischemic Cerebrovascular Disease in Qingdao
【摘要】 目的:分析本地缺血性脑血管病患者颅外颈动脉粥样硬化斑块的发生率,好发部位,斑块类型,两者之间的关系,了解本地区缺血性脑血管病患者颅外颈动脉粥样硬化的情况。方法:选择入院的135例急性缺血性脑血管病患者(包括脑梗塞患者90人和短暂性脑缺血发作患者45人为患病组)和同期门诊常规查体者30人(对照组),分别应用颈动脉彩超检测颅外颈动脉,检测其粥样硬化斑块发生率,好发部位,斑块类型。结果:患病组颅外颈动脉粥样硬化斑块的检出率(75.6%)与对照组(46.7%)比较,有显著性差异(P<0.01),脑梗塞(CI)患者颅外颈动脉粥样硬化斑块的检出率(76.7%)和短暂性脑缺血发作(TIA)患者(73.3%)比较无显著性差异(P>0.05)。患病组颅外颈动脉重度狭窄率(28.1%)与对照组(3.3%)比较有显著性差异(P<0.01),TIA患者颅外颈动脉重度狭窄率和正常对照组比较无显著性差异(P>0.05),CI患者与TIA患者颅外颈动脉重度狭窄率相比无统计学意义(P>0.05)。患病组与对照组斑块的好发部位均为颈总动脉分叉处(39.3%和35.0%),以硬斑(49.2%和65.5%)为主,两组不稳定斑块的比例(39.3%和20%)比较无显著性差异(p>0.05)。结论:①颅外颈动脉粥样硬化斑块是本地缺血性脑血管病人的病因之一。②本地缺血性脑血管病病人颅外颈动脉狭窄率较以往有增加。③颅外颈动脉粥样硬化斑块好发于颈总动脉分叉处,本地人群斑块可能以稳定性斑块为主。
【Abstract】 Objective: To comprehend the condition of extracranial arteries carotis in the local patients with ischemic cerebrovascular disease,we analysed the incidence rate,predilection site and plague types of extracranial carotid arteriosclerotic plaque.Methods: To choose 135 admitted patients(disease group) with acute ischemic cerebrovascular disease and 30 health examination persons(control group) from out-patient clinic at the corresponding time period.To check the incidence rate,predilection site,plaque types of arteriosclerosis of arteries carotis by carotis color ultrasonography.Results: The detection rate(75.6%) of external carotid arteriosclerotic plaque in disease group was significantly higher than the one(46.7%) of control group (p<0.01).The detection rate(76.7%) of extracranial carotid arteriosclerotic plaque in cerebral infarction disease group was similar to the one(73.3%) of transient ischemia attach(TIA) group(P>0.05).The severe stenosis rate(28.1%) of artery in disease group was significantly higher than the one(3.3%) of control group(P<0.01),while the severe stenosis rate of TIA group was similar to the one of control group(P>0.05),and also similar to the one of CI group(P>0.05).The predilection site of plaque in disease group(39.3%) is crotch of arteria carotis communis.,which was the same as control group(35.0%).The primary plaque type of disease group(49.2%) and control group(65.5%) was hard plaque.The compare for the instable plaque of disease group(39.3%) and control group(20%) had no significant difference(P>0.05).Conclusion:①arteriosclerosis plaque of extracranial arteries carotis is one of the causes of ischemic cerebrovascular disease in the local patients.②The local stenosis rate of extracranial carotid artery in patients with ischemic cerebrovascular disease now is higher than that in the past.③The predilection site of extracranial carotid arteriosclerotic plaque is crotch of arteria carotis communis.The primary plaque type of local people may be stable plaque.
【Key words】 Artherosclerosis; Arteria carotis; Ischemic cerebrovascular disease;
- 【文献出处】 河北医学 ,Hebei Medicine , 编辑部邮箱 ,2007年01期
- 【分类号】R743.3
- 【下载频次】46