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反复脑梗死患者服阿司匹林后血小板聚集功能的变化
Platelet aggregation function changes of recurrent cerebral infarction patients on aspirin
【摘要】 目的比较反复脑梗死患者同一次脑梗死患者服用阿司匹林后血小板聚集功能的差异,来探讨阿司匹林预防脑血管方面的作用。方法40名至少二次脑梗死的患者和28名一次脑梗死的患者服用阿司匹林(100 mg/d)至少7天以上,用二磷酸腺苷和花生四烯酸作诱导剂,测定血小板聚集功能。结果花生四烯酸作诱导剂时,反复脑梗死患者同一次脑梗死患者的血小板聚集功能有显著差异(P<0.01)。结论服用阿司匹林需检测血小板聚集功能,反映阿司匹林能否有效预防脑梗死复发。
【Abstract】 Objective To investigate cerebrovascular prevention of aspirin by comparing platelet aggragation function of recurrent cerebral infarction patients with only once cerebral infarction patients.Methods Forty recurrent cerebral infarction patients and only once cerebral infarction patients took aspirin(100 mg/d) for at least seven days.The patients’ platelet aggregation function were evaluated by adenosine disphosphate(ADP) and arachidonic acid(AA).Results Platelet aggregation function evaluated by arachidonic acid was significantly difirent between recurrent cerebral infarction patients and only once cerebral infarction patients.Conclusion Platelet aggregation function of the patients on aspirin should be measured.Because it can show whethert aspirin effectively prevent recurrence of cerebral infarction.
- 【文献出处】 中国实验诊断学 ,Chinese Journal of Laboratory Diagnosis , 编辑部邮箱 ,2006年03期
- 【分类号】R743.3
- 【被引频次】8
- 【下载频次】124