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不良妊娠结局妇女弓形虫感染的调查分析

Investigation on Toxoplasma gondii infection among women with abnormal pregnant result

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【作者】 崔黎明宗珊李淑红戴培左文静

【Author】 CUI Li-ming~(1),ZONG Shan~(1),LI Shu-hong~(1),DAI Pei~(1),ZUO Wen-jing~(2) (1.Department of Pathogenobiology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China;2.Department of Cell Biology,School of Basic Medical Sciences,Jilin University Changchun 130021,China)

【机构】 吉林大学基础医学院病原生物学教研室吉林大学基础医学院细胞生物学教研室 吉林长春130021吉林长春130021

【摘要】 目的探讨弓形虫感染与不良妊娠结局的关系。方法采用酶联免疫吸附实验法,检测长春地区93名有流产、畸形等不良妊娠结局的孕产妇(实验组)及107名正常孕产妇(对照组)血清弓形虫抗体,进行两组间感染率差异的分析。结果弓形虫抗体阳性率实验组(19.35%,18/93)明显高于对照组(5.61%,6/107)(P<0.01)。结论弓形虫感染是流产、畸形等不良妊娠结局的原因之一。

【Abstract】 Objective To discuss the relationship between the Toxoplasma gondii infection and the abnormal pregnant results.Methods ELISA was used to detect anti-T.gondii antibody in sera from 93 women with the abnormal pregnant results(experimental group) and 107 normal bearing women(control group).The difference of the infection rate of T.gondii between the two groups was statistically analyzed(χ2test).Results The positive rate of anti-T.gondii antibody in experimental group was 19.35%(18/93),and in control group with 5.61%(6/107).There was remarkable difference between two groups(P<0.01).Conclusion T.gondii infection may be one of the factors causing the abnormal pregnant results.

【基金】 吉林省科技厅项目(吉科合字No.19980300);长春市科技局资助课题(长春市科技厅No.20037)
  • 【文献出处】 中国病原生物学杂志 ,Journal of Pathogen Biology , 编辑部邮箱 ,2006年05期
  • 【分类号】R714.2
  • 【被引频次】11
  • 【下载频次】109
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