【摘要】 目的探索预防腮腺肿瘤术后Frey综合征发生的临床方法。方法将100例因腮腺肿瘤于2001年至2004年在我院接受腮腺浅叶或全腮腺切除术的患者分为研究组和对照组,每组各50例。研究组在腮腺及肿瘤切除术将结束时,在腮腺术床面神经各分支表面与皮瓣之间插入胶原蛋白片,作为隔离填充,阻止神经错位生长。对照组术中不植入隔离物,其他方面与研究组匹配。术后半年以上,用同一问卷收集患者资料,进行分析评价。结果随访时间为10～39个月,平均16个月。研究组Frey综合征发生率为20％(10／50),对照组为60％(30／50)(X2=15．04,P<0．001),术后颜面轮廓明显凹陷畸形的出现率两组分别为44％和80％(X2=12．26,P<0．001)。结论这种手术方式将Frey综合征的发生率由60％降至20％,为腮腺术后Frey综合征的预防提供了一种简单而有效的方法,同时患者术后颜面轮廓畸形也获得明显改善。更多还原

【Abstract】 Objective To investigate the prevention of Frey syndrome after parotidectomy. Methods A prospective cohort study of 100 patients with parotid cancer who received parotid surgery was underwent in our hospital from 2001 to 2004. These patients were assigned to two groups, study group(50 cases) and control group (50 cases). The patients in the study group received parotidectomy and intraoperative placement of collagen pieces within the parotid bed, between the skin flap and the facial nerve. The patients in the control group received a conventional parotidectomy and no collagen pieces was implanted. All of the patients were followed-up and were evaluated for Frey syndrome with identical questionnaires. Results Comparted with control group, the incidence rate of Frey syndrome was significantly decreased in the study group ( 20% vs 60% , X2 = 15. 04, P < 0. 001 ) . Postoperative incidence of facial contour apparente deformity was 80% (40/50) in control group and 44% ( 22/50 ) in study group (X2 = 12. 26,P < 0.001 ). Conclusions Use of collagen pieces as an interposition fill barrier improves parotidectomy outcome by reducing the incidence of Frey syndrome, and it improves cosmetic results concurrently.更多还原