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对叶大戟化学成分的研究

Studies on chemical constituents of Euphorbia sororia

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【作者】 张维库杨国恩李茜张晓琦叶文才

【Author】 ZHANG Wei-ku~1,YANG Guo-en~1,LI Qian~1,ZHANG Xiao-qi~2, YE Wen-cai~(1,2)(1.Department of Phytochemistry,China Pharmaceutical University,Nanjing 210038,China;2.Institute of Traditional Chinese Medicine & Natural Products,Jinan University,Guangzhou 510632,China)

【机构】 中国药科大学天然药物化学教研室暨南大学中药及天然药物研究所中国药科大学天然药物化学教研室 江苏南京210038江苏南京210038广东广州510632

【摘要】 目的:研究对叶大戟Euphorbia sororia的化学成分。方法:采用硅胶、Sephadex LH-20柱分离纯化,通过理化常数和光谱数据鉴定化合物的结构。结果:从对叶大戟乙醇提取物的醋酸乙酯部位中分离得到10个化合物,经理化常数和波谱数据分析,分别鉴定为山柰酚(kaempferol,1),莨菪亭(scopoletin,2),山柰酚3-O-吡喃葡萄糖苷(kaempferol 3-O-glucopyranoside,3),槲皮素(quercetin,4),香草酸(van illic ac id,5),反式对羟基肉桂酸(E-p-hy-droxy-c innam ic ac id,6),原儿茶酸(protocatechu ic ac id,7),6,7-二羟基香豆素(6,7-d ihydroxycoum arin,8),β-谷甾醇(-βsitosterol,9),胡萝卜苷(daucosterol,10)。结论:化合物1~10均为首次从该植物中分离得到。

【Abstract】 Objective: To study the chemical constituents of the aerial parts of Euphorbia sororia.Method: Isolation and purification were carried out by silica gel and Sephadex LH-20 column chromatographies.Compounds were identified by physicochemical properties and spectral analysis.Result: Ten compounds were isolated from the plant.Their structures were identified as kaempferol(1), scopoletin(2),kaempferol 3-O-glucopyranoside(3),quercetin(4), vanillic acid(5),E-p-hydroxycinnamic acid(6),protocatechuic acid(7),6,7-dihydroxycoumarin(8), β-sitosterol(9),and daucosterol(10),respectively.Conclusion: All the above compounds were isolated from the plant for the first time.

【关键词】 对叶大戟化学成分
【Key words】 Euphorbia sororiachemical constituents
  • 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,2006年20期
  • 【分类号】R284.1
  • 【被引频次】58
  • 【下载频次】535
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