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海金沙草中一个新的甾体苷类化合物的分离和结构鉴定(英文)
A new steroidal glycoside from Lygodium japonicum
【摘要】 目的:研究海金沙草(Lygodium japonicum)的化学成分。方法:采用硅胶柱层析、Sephadex LH-20柱层析、ODS柱层析等方法进行分离和纯化化学成分,结合化学方法和波谱方法进行结构鉴定。结果:从海金沙草中分离得到4个化合物,分别为:(24R)-stigmastan-3β,5α,6-tβriol 3-O-β--Dglucopyranoside(1),6-O-p-coumaroyl-D-glucopyranose(2),6-O-caffeoyl-D-glucopyranose(3),and 1-O-(E)-caffeoyl-β-D-gentiobiose(4)。结论:化合物1为新化合物,化合物2,3,4为首次从海金沙科中分离得到。
【Abstract】 Aim:To investigate the chemical constituents from the aerial parts of Lygodium japonicum.Methods:Various chromatographic techniques were employed for isolation and purification of the constituents.The structures were elucidated by chemical evidence and spectral methods.Results:A new stigmasterol glycoside,(24R)-stigmastan-3β,5α,6β-triol 3-O-β-D-glucopyranoside(1),together with three known phenolic glycosides:6-O-p-coumaroylD-glucopyranose(2),6-O-caffeoyl-D-glucopyranose(3),1-O-(E)-caffeoyl-β-D-gentiobiose(4) were obtained and identified by spectroscopic methods.Conclusion:All compounds were isolated from Lygodiaceae for the first time.
【Key words】 Lygodium japonicum; Lygodiaceae; stigmasterol glycoside; phenolic glycoside;
- 【文献出处】 中国药科大学学报 ,Journal of China Pharmaceutical University , 编辑部邮箱 ,2006年06期
- 【分类号】R284
- 【被引频次】18
- 【下载频次】379