【摘要】 目的:观察复方甘草酸苷抗乙肝病毒所致肝纤维化的临床疗效。方法:将118例慢性乙肝患者随机分为A、B组,A组给予复方甘草酸苷及基础保肝药物治疗,B组仅给予基础保肝药物治疗,均治疗12wk。观察治疗前、后2组血清玻璃酸酶、层粘连蛋白、Ⅲ型前胶原肽、Ⅳ型胶原的变化。结果:治疗后A组4项指标与B组相比均明显降低,具有显著性差异(P<0·05)。结论:复方甘草酸苷是治疗乙肝病毒所致肝纤维化有效药物之一。更多还原

【Abstract】 OBJECTIVE:To study clinical efficacy of Stronger Neo-Minophagen C(SNMC)in the treatment patients with hepatic fibrosis caused by hepatitis B virus.METHODS:118chronic HB patients were divided into2groups randomly,patients in group A received SNMC and basic treatment,in group B received basic treatment,all for12weeks,4marks of hepatic fibrosis(hyaluronic acid,laminin,typeⅢprocollagen peptide,typeⅣcollagen)were determined before and after treat-ment.RESULTS:Compared with group B,4marks of hepatic fibrosis were obviously reduced in group A after treatment,which were significantly differences between2groups(P<0.05).CONCLUSIONS:SNMC may be one of clinical practical value in tr_ eatment hepatic fibrosis caused by hepatitis B virus.更多还原