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盐酸托烷司琼预防妇科患者术后自控硬膜外镇痛致恶心、呕吐的临床疗效观察

Tropisetron in the Prevention of Postoperative Nausea and Vomiting Induced by Patient-Controlled Epidural Analgesia in Gynopathic Patients:Observation of Curative Effects

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【作者】 陈杰甘建辉

【Author】 CHEN Jie,GAN Jianhui(Dept.of Anesthesiology,Hebei Provincial Tangshan People’s Hospital,Tangshan063000,China)

【机构】 河北唐山市人民医院麻醉科河北唐山市人民医院麻醉科 唐山市063000唐山市063000

【摘要】 目的:观察盐酸托烷司琼用于预防妇科患者术后自控硬膜外镇痛(PCEA)致恶心、呕吐的效果。方法:将120例妇科手术后均行PCEA的患者随机分为2组,T组为盐酸托烷司琼组,N组为对照组,每组60例,观察2组用药后的恶心、呕吐发生率。结果:T组48h内恶心、呕吐发生率明显低于N组(P<0.05)。结论:盐酸托烷司琼预防妇科术后PCEA患者恶心、呕吐的发生安全、有效。

【Abstract】 OBJECTIVE:To observe the curative effect of tropisetron in the prevention of postoperative nausea and vomˉiting caused by patient-controlled epidural analgesia(PCEA)in gynopathic patients.METHODS:120patients who had unˉdergone patient-controlled epidural analgesia(PCEA)after gynopathic operation were randomly divided into2groups:60in group T were assigned to receive tropisetron,and60in group N as control,the incidences of nausea and vomiting in the two groups after medication were observed.RESULTS:There were significantly lower incidences of nausea and vomiting within48h in group T than in the placebo group(group N)(P<0.05).CONCLUSIONS:Tropisetron is safe and effective in the prevention of PCEA in gynopathic patients.

  • 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2006年13期
  • 【分类号】R614
  • 【被引频次】4
  • 【下载频次】88
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