【摘要】 目的探讨孕妇弓形虫感染经胎盘垂直传播的情况。方法采用酶联免疫吸附试验三联诊断法对93例孕妇和新生儿血清标本进行弓形虫感染的血清学检测。结果孕妇弓形虫各单项检测阳性率分别为循环抗原(CAg)8.6%,IgM 10.8%,IgG 36.6%,新生儿组分别为CAg 4.3%,IgM 2.2%,IgG 15.1%;孕妇弓形虫平均感染率为45.2%,新生儿弓形虫平均感染率为19.4%;平均垂直传播率为42.9%,孕妇IgG垂直传播率为41.3%,CAg垂直传播率为50%。结论孕妇是弓形虫感染高危人群,通过胎盘垂直传播感染胎儿的危险性很高,应对孕妇开展血清学监测及时采取措施,有效地预防先天性弓形虫感染。更多还原

【Abstract】 Objective To investigate the relationship and status of toxoplasma(Tox) infection between pregnant women and their fetus.Methods Enzym-linked immunosorbent assay(ELISA) was used to detect circulating antigen(CAg),special antibodies IgM and IgG in the blood of pregnant women and fetal umbilical blood.Results Among the 93 cases,8 were TOX-CAg positive(8.6%),10 were TOX-IgM positive(10.8%)and 34 were TOX-IgG positive(36.6%) in pregnant women;the three were TOX-CAg 4(4.3%),TOX-IgM 2(2.2%)and TOX-IgG 14(15.1%) respectively in newborn infants.The overall prevalence rates of toxoplasmosis among the pregnant women and their newborn infants were 45.2%(42/93)and 19.4%(18/93) respectively.the total proportion of vertical transmission was 42.9%,the IgG was 41.3%,the CAg was 50%.Conclusion Pregnant women are at the high risk of toxoplasma infection,and more than 1/3 fetus will get infection from their mother before they give birth.Therefore,Sero-epidemiologic survey in pregnant women should be strengthened in better child-bearing.更多还原