【摘要】 目的:探讨中心减压自体骨与骨形态发生蛋白(BMP)植入治疗缺血性股骨头坏死的临床疗效。方法:缺血性股骨头坏死36例41髋,男25例29髋,女11例12髋;年龄31~69岁,平均45·5岁。按Ficat分期0期3髋、Ⅰ期19髋、Ⅱ期13髋、Ⅲ期6髋,行中心减压自体骨与BMP植入术。结果:36例患者均获随访,随访时间2~63个月,平均41个月。以广州中医药大学附属医院提出的疗效标准百分法评价治疗效果,优21例,良8例,可4例,差3例。结论:此术式可有效降低骨内压,改善股骨头血供,植入自体松质骨对关节软骨起到有效支撑防止塌陷的作用。BMP诱发组织修复,加快了股骨头骨质修复的过程,适于Ficat分期0~Ⅱ期的早期患者。更多还原

【Abstract】 Objective:To explore the therapeutic effect of center decompression and autogenous bone and BMP implantation in treating ischemic necrosis of femoral head(INFH).Methods:Forty-one hips in 36 patients with ischemic necrosis of femoral head were included 29 hips of 25 female and 12 hips of 11 male,and the average age of all the patients was 45.5 years ranging from 31 to 69 years.According to Ficat Staging system,3,19,13 and 6 hips were at 0,Ⅰ,Ⅱ and Ⅲ stages respectively.All patients were treated by center decompression and autogenous bone and BMP implantation.Results:All patients were followed up for 2 to 63 months (average 41 months).According to evaluating standard of curative effect set by the Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,the excellent result was achieved in 21 case,good in 8 cases,fair in 4 cases and poor in 3 cases.Conclusion:The method of center decompression and autogenous bone and BMP implantation can decrease bone pressure,improve blood supply to femoral head.The implantation with autologous spongy bone can support effectively articular cartilage and prevent collapse.BMP can induce tissue repair,speed up the bone reconstruction of femoral head.This method is effective in the treatment of the cases at Ficat Staging 0-Ⅱ.更多还原