【摘要】 目的探讨早期超敏C反应蛋白(hs-CRP)含量与脑梗死病情进展的关系。方法对经头颅CT或磁共振成像(MRI)证实的急性缺血性脑梗死患者于发病24h内与7d采用化学发光免疫法测定hs-CRP,采用加拿大卒中量表对发病后48h病情发展变化进行评定,根据评分结果分为进展性与非进展性脑梗死两组。结果进展性脑梗死患者血清hs-CRP水平明显高于非进展性患者(P<0.01),发病后24h的血清hs-CRP水平高于7d的水平(P<0.01)。结论hs-CRP与脑梗死所致神经功能损害程度密切相关,早期检测可以为脑梗死的病情变化提供有用的信息。更多还原

【Abstract】 Objective To study the relationship between high sensitive C-reactive protein (hs-CRP) and the progress of cerebral infarct. Methods The levels of hs-CRP were measured in 24 hours and seven days after using chemiluminescence immunoassay in the patients of acute ischemic stroke who were diagnosed by CT or MRI. The disease progress were valued by Canadian neurological scale in 48 hours after cerebral ischemic stroke.The patients were divided into progressing group and no-progressing group. Result The serum levels of hs-CRP in the progressing group were significantly higher than that in the no-progressing group(P<0.01). The serum levels of hs-CRP in 24 hours were significantly higher than that after 7 days(P<0.01). Conclusion The level of hs-CRP is closely associated with the degree of the neurological damage caused by ischemic stroke. It can provide useful information for cerebral infarct.更多还原