【摘要】 目的探索布比卡因腰麻用于剖宫产手术的最佳剂量。方法选择80例剖宫产手术,分别用0．75％布比卡因2. 0mL(A组20例)、1．5mL(B组20例)、1．2mL(C组20例)、1．0mL(D组20例)进行腰麻,观察麻醉显效时间、镇痛质量、麻醉平面、维持时间、运动阻滞程度、麻醉后低血压、恶心呕吐情况、产妇术后头痛发生率及新生儿Apgar评分。结果四组麻醉显效时间差异无显著性(P>0．05);镇痛质量D组与A组比较差异有显著性(P<0．05);麻醉平面维持时间D组与A组及 B组比较差异显著(P<0．01或P<0．05);运动阻滞程度C、D两组与A组比较明显较轻(P<0．05或P<0．01),D组有阻滞不全、肌松不良表现;麻醉后低血压、恶心呕吐副作用发生率C、D组明显低(P<0．05或P<0．01)。结论 0．75％布比卡因腰麻剖宫产手术的最佳剂最为1．2mL。更多还原

【Abstract】 AIM To observe the best dose of Bupivacaine in lumbar anesthesia for cesarean section. Methods The 80 full-term puerperas of cesarean section with lumbar anesthesia were randomly divided into four groups: group A(20 cases,0.75% Bupivacaine 2.0 mL),group B (20 cases,0.75% Bupivacaine 1.5 mL),group C (20 cases, 0.75% Bupivacaine 1.2 mL) and group D (20 cases,0.75% Bupivacaine 1.0 mL).Anesthesia induction time,pain control,anesthesia level holding time,motor nerve depression,MAP and SPO2 level,the rate of headache of the pueroeras in postoperation and newborn Apgar score were compared among the four groups.Rsults There was no significant difference in the time of anesthesia inductin,the rate of headache of the pueroeras in postoperation and newborn Apgar score among the four groups.The pain control in group A was significantly better than it in group D(P<0.05). Anesthesia level holding time was significantly longer in group A and in group B as compared with it in group D(P <0.01 or P<0.05).Motor nerve depression was significantly lighter in group C and in group D as compared with it in group A (P<0.05 or P<0.01). The incidences of side-effects were lower in group C and in group D as compared with those in group A (P<0.05 or P<0.01).Conclusion The best dose of 0.75% Bupivacaine in lumbar anesthesia for cesarean section is 1.2mL.更多还原