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间断反复洗胃联合胃肠负压引流抢救急性有机磷农药中毒的应用研究

A CLINICAL STUDY ON THE EFFECTS OF INTERMITTENT AND REPEATED GASTRIC LAVAGE AND GASTROENTERIC DRAINAGE IN SAVING ACUTE ORGANOPHOSPHORUS PESTICIDE POISONING(AOPP)

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【作者】 唐雄修黄翠莲汪克林石秋连

【Author】 TANG Xiongxiu,HUANG Cuilian,WANG Kelin,et al Huaiji People’s Hosptal,Huaiji 526400 PRC

【机构】 怀集县人民医院怀集县人民医院 广东怀集526400广东怀集526400

【摘要】 目的探讨急性有机磷农药中毒(AOPP)病人洗胃的最佳方法。方法83例AOPP病人在常规洗胃的基础上,行间断反复洗胃联合胃肠负压引流,以73例常规治疗者为对照。比较两组病死率、胆碱酯酶上升至正常的30%和50%的时间、反跳、中间综合征及住院周期。结果两组病死率、CHE上升至正常的30%和50%的时间、反跳、中间综合征及住院周期都存在差异性(p<0.05)。结论间断反复洗胃联合胃肠负压引流可及时、有效地清除AOPP病人胃肠道的毒物,可提高急性有机磷农药中毒的抢救成功率,降低病死率,缩短住院周期,减少反跳及中间综合征的发生。

【Abstract】 Objective To explore the best way of gastric lavage in the patients with AOPP.Methods 156 patients with AOPP were randomly divided into two groups.The patients of control group(73 cases)received routine treatment,the observation group(83 cases)was added intermittent and repeated gastric lavage and gastroenteric negative pressure drainage.The change of the case fatality,time of cholinestrase(CHE)recover to 30% and 50% common level,rebound,intermediate syndrome and the hospital stay were observed.Results The case fatality,rebound and intermediate syndrome were significantly reduced in the observation group,and the time of CHE recover to 30% and 50% common level and the time of hospital stay were remarkably shorted(p<0.05).Conclusion Intermittent and repeated gastric lavage and gastroenteric negative pressure drainage can timely and effectively eliminate gastroenteric poison,and can effectively enhance the successful rate,lower mortality,short hospital stay and reduce rebound and intermediate syndrome.

【基金】 2006年肇庆市科技创新计划项目(项目编号:2006E117)
  • 【文献出处】 现代医院 ,Modern Hospital , 编辑部邮箱 ,2006年12期
  • 【分类号】R595.4
  • 【下载频次】28
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