【摘要】 目的探讨老年人糖耐量低减(IGT)患者的代谢改变和临床表现。方法观察一组30例50岁以上IGT患者的临床表现与生化指标,与同年龄段的2型糖尿病(DM)和正常对照(NGT)人群进行比较研究。结果IGT组合并高血压、脑血管病者显著高于NGT组,但低于DM组,而合并冠心病者与NGT组、DM组相比差异无显著意义;IGT组甘油三酯(TG)、尿微白蛋白排泄率(UAER)显著高于NGT组,但低于DM组,差异有显著性(p<0.01)。结论老年人IGT患者不仅有糖代谢异常,而且也存在着脂代谢紊乱,与正常人群相比有较高的心脑血管疾病和肾病的发病率。更多还原

【Abstract】 Objective To investigate the metabolic change and clinical manifestation in elder patients with impaired glucose tolerance (IGT). Methods The clinical manifestation and biochemistry index of a group of 30 patients over 50 were compared with those of people with T2DM and normal individual (NGT) in same age. Results The incidence of hypertension and CVD in IGT group was significantly higher than that in NGT group,but lower than that of DM group. The IGT group showed no significant difference of CHD incidence compared with group NGT and DM. The TG and UAER were significant higher in group IGT than NGT but lower than group DM,which has significant difference (p<0.01). Conclusion The elder IGT patients had carbohydrate metabolism and lipid metabolisic disorder,also had higher risk of cardiovascular disease and nephropathy than in normal group.更多还原