【摘要】 溶栓疗法是血栓性疾病安全有效的治疗手段,开发安全高效、廉价的新型纤溶酶对于预防与治疗血栓性疾病具有重要意义。近年来,在日本纳豆、韩国大豆酱、中国豆豉、发酵虾酱等许多亚洲传统发酵食品中均发现有丰富的纤溶酶资源,这些食品微生物分泌的纤溶酶安全、高效,是潜在的溶栓剂。重点介绍传统发酵食品中发现的纤溶酶的理化性质、溶栓特性及其潜在应用。更多还原

【Abstract】 Thrombolytic therapy is a safe and effective way to cure thrombosis. Developing the safe,effective and cheap therapeutic thromolytic agents are important to prevent and cure thrombosis. In recent years,several fibrinolytic enzymes have been found in the resources of Asian traditional fermented foods,such as Japanese natto,Korea Chungkook-Jang,Chinese Douchi and fermented shrimp paste. These fibrinolytic enzymes secreted by food-grade microorganisms are safe and effective,and are potent thrombolytic agents. The physical and biochemical properties,thrombolytic characteristics,and the potential applications of these fibrinolytic enzymes from Asian fermented food,are reviewed.更多还原