【摘要】 目的:观察和分析全膝关节置换术后假体周围骨密度的变化情况。方法:应用双能X线骨密度仪(DEXA)观察16例患者全膝关节置换术后1周、3个月、6个月、12个月时股骨和胫骨假体周围的骨密度。股骨假体周围分为4个兴趣区,胫骨假体周围分为3个兴趣区,对各个区内的平均骨密度变化进行观察和分析。结果:术后12个月内假体周围各分区平均骨密度均有显著的降低(P<0.05),股骨假体周围骨密度平均降低15.73%,胫骨假体周围平均降低15.16%,术后前3个月内骨密度降低最为显著。结论:全膝关节置换术后假体周围骨密度明显降低。采用DEXA可以早期、准确的观测骨密度变化。更多还原

【Abstract】 Objective:To evaluate the changes of periprosthetic bone mineral density(BMD) after total knee arthroplasty.Methods: Sixteen patients treated by cemented total knee arthroplasty were included in this study.The periprosthetic bone mineral density was measured by dual-energy X-ray absorptiometry 1 week,3 months,6 months and 12 months postoperatively.The periprosthetic bone of distal femur and proximal tibia were divided into four and three regions of interest separately,and the mean BMD was measured.Results: The mean BMD of all seven regions decreased within 12 months after operation(P<0.05) and of distal femur and proximal tibia decreased by 15.73% and 15.16%,respectively.Bone loss was the most rapid during initial 3 months.Conclusions: The periprosthetic bone mineral density significantly decreases after total knee arthroplasty,which may be measured precisely by dual-energy X-ray absorptiometry.更多还原