【摘要】 目的:探讨乙型病毒性肝炎肝硬化患者健康相关生活质量,并分析其影响因素。方法:采用简明生命质量测定量表(SF-36)中文版对120例乙肝肝硬化患者的生活质量进行测量,对其影响因素进行单因素分析和多因素logistic回归分析,并与正常人群进行对比。结果:除心理功能维度外,肝硬化患者生活质量各维度均低于对照组(P<0.001);Child分级主要影响生理健康方面的评分,而性别对生理及心理健康方面评分均有影响。结论:肝硬化患者生活质量普遍下降,其主要影响因素为性别与Child分级。更多还原

【Abstract】 Objective: To explore factors associated with health-related quality of life(HRQOL) in patients with HBV-related liver cirrhosis.Methods: A cross-sectional study in which 120 patients′ demographic and clinical characteristics were documented and their HRQOL was conducted by using the Chinese version of Short Form-36.The association of HRQOL impairment with clinical parameters was compared between patients and normal persons by univariate analysis and multiple logistic stepwise regression.Results: In all except one domains(mental health) of SF-36,HRQOL scores were significantly lower in the patient group than in the control group(P<0.001);Child class was mainly associated with score in Physical Component Summary(PCS) while gender affected both PCS and Mental Component Summary(MCS) score.Conclusion: HRQOL of patients with liver cirrhosis is impaired obviously.The score is further affected by gender and Child class.更多还原