【摘要】 目的了解本区学龄前儿童乙肝表面抗体(抗-HBs)的情况,以便更好地保护学龄前儿童免受乙肝病毒侵袭。方法对佛山市禅城区30家幼儿园全程接种乙肝疫苗的1~6岁儿童采用手指微量血检测抗-HBs。结果采用微量血监测儿童抗-HBs方法较易被接受,全程接种乙肝疫苗的儿童1~3年内抗-HBs刚性率较高,随着接种疫苗间隔时间的延长抗-HBs刚性率下降明显,从1~3岁时的89.9%下降到3~4岁时的61.2%。结论全程接种乙肝疫苗的儿童抗-HBs刚性率会随着接种疫苗间隔时间的延长而下降,每年检测一次抗-HBs,当抗-HBs水平低于保护性以下时,应加强接种疫苗。特别是3~4岁时加强一针比较合理。更多还原

【Abstract】 Objective to monitor the immue effect of hepatitis B vaccine with themicroperipheral blood measurement.Method Usingthe micro peripheral blood to measurethe HbsAb level of children from 30 kindergartens of chan cheng district in three years.Result This methodis easily accepted.in this children,the HbsAb positive rate iS highafter vaccinate the hepatitis B vnccine one or three years,but laterit will fall obviously,for example,from one to three to three to four age,the positive rate will fallfrom 89.9%to 61.2%.Conclusion After vaccinate the hepatitis B vaccine,the time is longer,the HbsAblevel is lower,so to check the HbsAb level once a year,and when the HbsAblevel is lower than the protective level,the children should intensify vaccinating vaccine,especially to takethe boosterinection in four age iS reasonable.更多还原