【摘要】 目的:探讨老年人脑电图(EEG)与认知功能的关系。方法:对569名老年人进行EEG 检查及认知功能测验,用选自韦氏成人智力量表(WAIS-R)的算术、数字广度、填图、木块图以及简易智能状态检查表(MMSE)等五项测验逐个测量老年人的认知水平。在第一次测查一年后,对其中373 名老年人重复进行认知功能测查。结果:MMSE及数字广度测验的得分变化与各位点EEG θ、δ波功率值有关,MMSE:得分下降组基线θ、δ波功率值高于MMSE得分不变组,差异有统计学意义,主要以头后部各区(T3、T5,P3、O1,O2,T4、T6)为明显。T6处θ波功率为9．25μV2,对MMSE得分下降诊断的灵敏度为0．73,特异度为0．64。T3处θ波功率的增加为8．75μV2,对数字广度得分下降诊断的灵敏度为 0．75,特异度为0．56。结论:EEG θ波功率的增加对了解认知功能下降有重要的参考价值。更多还原

【Abstract】 Objective: To explore the relationship between EEG and cognitive decline in aged people. Methods: 569 aged people were surveyed by EEG examination and cognitive test including arithmetic, digit span, picture filling and block design. The cognitive tests were repeated twelve months later. Results:The decline of score of MMSE and digit span correlate with the EEG θ.δ power, the obvious difference of the channels in back head was statistically significant. The θ power of right back temporal can predict the decline of MMSE. The sensitivity is 0. 73, and the specificity is 0. 64 at the point 9. 25. The θ power of left middle temporal can predict the decline of digit span. The sensitivity is 0. 75, and the specificity is 0. 56 at the point 8. 75. Conclusions:The in crease of EEG θpower is of great importance in the diagnose of cognitive decline.更多还原