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注射用盐酸洛美沙星与奥硝唑氯化钠注射液配伍稳定性研究

Study on stability of compatibility of lomefloxacin hydrochloride for injection with ornidazole and sodium chloride injection

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【作者】 朱玲仙许凤娟

【Author】 ZHU Ling-xian,XU Feng-juan(Jiaxing Women and Infant Health Hospital,Jiaxing 314000,China)

【机构】 嘉兴市妇幼保健院嘉兴市妇幼保健院 嘉兴314000嘉兴314000

【摘要】 目的研究盐酸洛美沙星与奥硝唑氯化钠注射液的配伍稳定性。方法在室温(25℃)条件下,应用紫外分光光度法考察洛美沙星与奥硝唑氯化钠注射液配伍后6 h内的含量变化,并观察配伍液外观及pH值的变化。结果洛美沙星与奥硝唑氯化钠注射液配伍后外观、pH值及含量均无明显变化。结论注射用盐酸洛美沙星与奥硝唑氯化钠注射液在6 h内可以配伍使用。

【Abstract】 Objective To study the compatible stability of lomefloxacin hydrochloride with ornidazole and sodium chloride injection.Methods Changes in the content were determined by UV spectrophotometry within 6h after the compatibility of lomefloxacin hydrochloride and ornidazole and sodium chloride injection at room temperature(25 ℃).The variations in the appearance and pH of the compatible solution were observed by eye and acidimeter separately.(Results)The appearance,pH value,and the content of lomefloxacin and ornidazole had no change within 6h after the compatibility.Conclusion Both lomefloxacin hydrochloride for injection and ornidazole and sodium chloride injection can be compatiblely used,and it is stable within 6h.

  • 【文献出处】 实用药物与临床 ,Practical Pharmacy and Clinical Remedies , 编辑部邮箱 ,2006年04期
  • 【分类号】R942
  • 【被引频次】8
  • 【下载频次】68
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