【摘要】 神经内分泌免疫网络(NIM)是机体内多维立体网络调控机构,在多种自身免疫性疾病中起重要作用。本文综述了神经内分泌免疫网络中的下丘脑-垂体-肾上腺(HPA)、下丘脑-垂体-性腺(HPG)等对免疫系统的调节作用,讨论了神经内分泌免疫网络与多发性硬化(MS)及其动物模型即实验性变态反应性脑脊髓炎(EAE)的关系。提示神经内分泌免疫网络可能是其发生发展的重要机制之一。更多还原

【Abstract】 Neuroendocrine-immune network is a multi-dimensional modulating mechanism in human body, it plays an important part in many autoimmune diseases. The effect of hypothalamus- pituitary-adrenal axis, hypothalamus-pituitary-gonadal axis on the network of immune system were summarized. The relationship between neuroendocrine-immune network and the animal model of experimental allergic encephalomyelitis(EAE) was discussed.It suggests that neuroendocrine-immune network is one of important mechanisms in the development of EAE.更多还原