【摘要】 目的探讨血糖与脑梗死进展相关关系。方法急性脑梗死患者入院后查空腹血糖(FBG),按FBG大小分为A组(FBG<6mmol/L),B组(FBG6～10mmol/L),C组(FBG>10mmol/L),每组统计稳定型脑梗死和进展型脑梗死(ECI)例数,计算脑梗死进展率,用SPSS10.0统计软件对三组进行χ2检验。将血糖值以5、6、7、8、9、10、11mmol/L为界分为8组(每组包括下限),计算每组脑梗死进展率(ER),用Spearman等级相关系数rs检验FBG与ER相关性。结果A、B、C三组ER总体上存在着非常显著性差异(P<0.001),C组脑梗死进展率均高于A组和B组,差异有显著性(P<0.005,P<0.025)。FBG与ER之间存在显著性相关(P<0.02),血糖每升高1mmol/L,脑梗死进展率增加约4%～6%。结论FBG与ER相关,高血糖会促进脑梗死进展,二者可能互为因果,FBG≥10mmol/L可作为脑梗死进展的预测指标。更多还原

【Abstract】 Objective To analyse relation between fasting blood gluconate (FBG) and evolving cerebral infarction(ECI).Methods FBG of acute cerebral infarction (ACI) cases after they were admitted was tested and divided into three groups according its value:groupA,FBG<6mmol/L,group B,FBG 6～10mmol/L,group C,FBG≥10mmol/L.The numbers of ECI and completed cerebral infarction (CCI) were counted in each group respectively,so were evolving rate of ACI(ER).χ2 test was done by SPSS10.0 statistic software.Then FBG was divided into 8 groups by the site of FBG 5,6,7,8,9,10,11mmol/L according its value (each group including the lowest limit),calculated ER as well,tested the correlation by Spearman rs testing.Results There was very significant defference among the mentioned three groups (P<0.001),ER of group C was more than those of group A and B,the defference was significant(P<0.005,P<0.025).There was significant correlation also between FBG and ER(P<0.02),ER rised about 4～6% following each 1mmol/L FBG.Conclusion The value of FBG was correlated with ER,which would be raised by hyperglycemia,and in turn aggravated itself. It can be predictive marker of evolution of ACI that FBG is no less than 10mmol/L.更多还原