【摘要】 目的调查162例子宫颈病变患者宫颈组织高危型HPV感染情况,探讨高危型HPV感染与宫颈病变的关系。方法采用第二代杂交捕获技术检测2003年11月~2005年9月在我院行LEEP治疗的162例住院患者宫颈高危型HPV感染情况,并与病理诊断和分级进行回顾性分析。结果162例宫颈病变患者,其中慢性宫颈炎32例,CINⅠ42例,CINⅡ54例,CINⅢ34例。其高危型HPV感染率则分别为18.8%、61.9%、83.3%和85.3%。高度CIN的高危型HPV感染率明显高于低度CIN和慢性宫颈炎(P<0.05和0.001)。结论高危型HPV感染与宫颈病变的发生、发展有关,并随病变程度的加重,感染率增高。更多还原

【Abstract】 Objective Objective:To investigate the prevalence of high-risk HPV infection of 162 patients with cervical lesion and discuss their relation.Methods Using the HC-Ⅱ technique,HPV infection of 162 patients with cervical lesion were detected and were compared with their pathologic grade.Results Among 162 cases,32 were with chronic cervicitis,42 with CIN Ⅰ,54 with CIN Ⅱ,34 with CIN Ⅲ.HPV were positive in 6 of 32 patients with chronic cervicitis(18.8%),26 of 42 CIN I(61.9%),45 of 54 CIN Ⅱ(83.3%),29 of 34 CIN Ⅲ(85.3%),respectively.The positive rate was higher in high-grade CIN(CIN Ⅱ and CIN Ⅲ) compared with low-grade CIN(CIN Ⅰ)or chronic cervitis(P<0.05 and 0.001,respectively).Conclusion High-risk HPV infection were correspond with the onset and development of cervical intraepithelial neoplasia.The higher the lesion grade,the higher rate for HPV infection.更多还原