【摘要】 目的:探讨准分子激光原位角膜磨镶术(LASIK)手术前后眼压和眼压差的影响因素。方法:对271例行LASIK治疗且资料完整的近视眼患者进行研究,分析患者的性别、眼别、年龄、裸眼视力、术前眼压、近视度、散光度、术前中央角膜厚度和术中角膜切削厚度对LASIK术后眼压和手术前后眼压差的影响。结果:单因素相关分析表明LASIK术后眼压与性别、术前眼压、角膜切削厚度、裸眼视力和近视度呈显著性相关,而多因素分析仅发现前4项与其显著相关,其中术前眼压是最重要的相关因子。而单因素分析发现LASIK手术前后眼压差与性别、角膜切削厚度、术前视力、近视度和中央角膜厚度呈显著性相关,多因素分析则仅前2项和中央角膜厚度与其显著相关,其中角膜切削厚度是最重要的预测因子。结论:术前眼压,而不是中央角膜厚度是预测LASIK术后眼压最重要的因素。而性别和角膜切削厚度是术后眼压和手术前后眼压差的共同影响因素。更多还原

【Abstract】 Aim: To investigate the factors of affecting intraocular pressure(IOP) difference before and after LASIK,and IOP after LASIK. Methods: In this prospective cases series study,patient age,gender,preoperative visual acuity,preoperative central corneal thickness(CCT), preoperative IOP,myopia,astigmatism and ablation depth were studied to determine IOP and IOP difference in 271 consecutive cases who underwent LASIK.Results: The factors significantly correlated with postoperative IOP were gender,preoperative visual acuity,preoperative IOP,ablation depth and myopic diopter by univariate analysis,only the four former were its predictors by multivariate analysis,and preoperative IOP was the most important predictor.The predictors for IOP difference included gender,preoperative visual acuity,preoperative CCT,ablation depth and myopic diopter by univariate analysis,and only both of ablation depth,gender and preoperative CCT were its predictors by multivariate analysis,and the ablation depth was the most important predictor.Conclusions: Preoperative IOP,not preoperative CCT,was the most important predictors of IOP after LASIK.Gender and ablation depth were the common predictors of IOP difference before and after LASIK,and IOP after LASIK.更多还原