【摘要】 目的探讨抗抑郁剂药物辅以针对性心理治疗技术对有儿童受虐史抑郁症的疗效。方法对60例有儿童受虐史的抑郁症患者近似随机地分成心理治疗加药物治疗组和单用药物组,两组各30例,在治疗后1、2、4、6个月,评定两组的HAMD减分率和临床总体印象量表(CGI)中的疗效改善分值,并根据HAMD减分率和CGI的疗效改善分值来比较两组临床疗效。结果单一药物组和药物联合心理治疗组在治疗后1、2、4月时,两组的HAMD减分率及CGI的总体改善分值的差异无统计学意义(P>0.05)。6个月时,药物联合心理治疗技术组的HAMD减分率及CGI的总体改善分值均大于单一药物组,差异具有统计学意义(P<0.05)。结论短期内,心理治疗联合药物治疗组与单纯的药物治疗组相比,并未显示出较好的疗效,但远期效果好于单一的药物治疗。更多还原

【Abstract】 Objective To study the efficacy of special technique of psychotherapy with pharmacological treatment in depressive patients who had childhood abused experience. Methods A control study of special technique of psychotherapy with pharmacological treatment versus pharmacological treatment alone was done in 60 depressive patients who had childhood abused experience. 60 patients were randomly divided to two groups. 30 patients accepted special technique of psychotherapy and pharmacological treatment; another 30 patients accepted pharmacological treatment alone. All subjects were rated with Hamilton Rating Scale for Depression (HAMD), Clinical Global Impression (CGI), when pre-treatment, 1, 2, 4, 6 moths after treatment. Results There were no significant difference in score of reduce ratio of HAMD and CGI between special technique of psychotherapy with pharmacological treatment and pharmacological treatment alone, when 1, 2, 4, moths after treatment. But, there were significantly difference score of reduce ratio of HAMD and CGI in two groups when 6 moths after treatment. Conclusion The therapeutic effect between special technique of psychotherapy with pharmacological treatment and pharmacological treatment alone in depressive patients who have childhood-abused experience is same in short term (P>0.05). But, the long-term efficacy of the former is better than that of the latter (P<0.05).更多还原