【摘要】 目的:探讨糖类抗原19-9(CA19-9)、糖类抗原125(CA125)与肝纤维化的关系。方法:采用酶联免疫吸附试验(ELISA)检测108例慢性肝炎(CH)患者和20例正常人血清透明质酸(HA)、CA19-9、CA125水平。同时测定其肝功能相关指标并进行相关性分析。结果:慢性肝炎轻、中、重度组及肝硬化组血清CA19-9、CA125水平明显高于健康对照组(P<0.01)。与TBil、AST、GLB显著呈正相关,与ALB呈显著负相关(P<0.05或P<0.01)。结论:CA19-9、CA125可作为肝纤维化的早期诊断指标。更多还原

【Abstract】 Objective: To investigate the relations between amylose-antigen 19-9(CA19-9),anylase-antigen 125(CA125) and liver fibrosis.Methods﹕ The serum levels of HA﹑CA19-9 and CA125 in 108 cases of the patients with chronic hepatitis and 20 health persons were tested by ELISA﹒The relative indexes of liver function were determined at the same time.Results: The both CA19-9 and CA125 levels in serum of low middle high-grade chronic liverish patient group and hepatocirrhosis group were significant higher than health control(P<0.01).It showed positive correlation with Tbil,AST,GLB and negative correlation with ALB(P<0.05 or P<0.01).Conclusion: CA19-9﹑CA125 could be as early diagnostic indexes for liver fibrosis.更多还原