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不同分娩方式脐血生长激素水平的测定

Detection of growth hormone level in umbilical cord in different delivery mode.

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【作者】 孙念政; 纪洪生; 沈柏均;

【Author】 SUN Nian-zheng~1,JI Hong-sheng~2,SHEN Be-jun~1.(1 Qilu Hospital of Shandong University,Jinan,Shandong 250012,China;2 Shengli Hospital of Shandong,Jinan,Shandong 250000,China)

【机构】 山东大学齐鲁医院儿科; 山东省立医院麻醉科; 山东大学齐鲁医院儿科 山东济南250012; 山东济南250000; 山东济南250012;

【摘要】 【目的】探讨不同分娩方式对脐血生长激素(growth hormone,GH)的影响,以及脐血GH水平与胎儿生长发育的关系。【方法】取34例足月阴道产(其中20例脐动脉血)和23例剖宫产新生儿脐静脉血标本,以放射免疫分析法检测GH含量。应用SPSS 10.0软件进行t检验、直线相关分析。【结果】34例足月自然分娩组胎儿脐静脉血中GH含量为(32.29±16.58)μg/L,23例剖宫产组胎儿脐静脉组中GH含量为(20.3±7.50)μg/L,差异有非常显著性(P<0.01)。57例新生儿体重平均值为(3432±346)g,身高平均值为(48.87±1.59)cm,以直线相关关系分析,脐静脉血中GH含量与体重和身高均呈正相关关系(r分别为0.833、0.837,P均P<0.05)。【结论】不同分娩方式对脐血GH产生不同的影响;脐血中GH水平与胎儿的体格发育有密切的关系。

【Abstract】 【Objective】 To investigate the effect of different delivery mode on growth hormone(GH),and the relationship between GH level in umbilical cord and fetal physical development. 【Methods】 Umbilical vein blood from 34 full-term neonates from vaginal delivery(20 from umbilical artery) and 23 from selected cesarean section were selected for GH detection with Radio-Immunity Analysis Technique.T-test and linear correlation were used for statistics analysis. 【Results】(32.29±16.58) μg/L GH level was detected in vaginal delivery group and(20.3±7.50)μg/L GH level was detected in cesarean section group which showed significant difference(P<0.01).Mean neonatal weight of 57 cases was(3432±346)g and mean height was(48.87±1.59)cm.GH level in umbilical vein blood had positive correlationship with neonatal weight(r=0.833,P<0.05) and neonatal height(r=0.837,P<0.05). 【Conclusions】 GH level is different in vaginal delivery group and cesarean section group.There is close relationship between GH level in umbilical cord and fetal physical development.

【关键词】 脐血; 生长激素; 新生儿; 分娩方式;
【Key words】 umbilical cord blood; growth homone; neonate; delivery mode;
  • 【文献出处】 中国儿童保健杂志 ,Chinese Journal of Child Health Care , 编辑部邮箱 ,2006年04期
  • 【分类号】R174
  • 【被引频次】2
  • 【下载频次】63
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