【摘要】 目的探讨阻塞性睡眠呼吸暂停低通气综合征(obstructivesleepapneahypopneasyndrome,OSAHS)患者口咽局部截面积与多导睡眠描记(polysomnography,PSG)监测指标是否具有相关性,是否可以作为病情轻重的推测指标及悬雍垂腭咽成形术(uvulopalatopharyngoplasty,UPPP)的指导指标,手术前后的变化值是否可以作为疗效的预测指标。方法电子喉镜摄像和图形处理获得20例OSAHS患者手术前后及20例无鼾者的口咽局部截面积,OSAHS患者手术前后行PSG监测。结果①OSAHS患者口咽局部截面积较无鼾者狭窄(P﹤0.01);②口咽局部截面积与睡眠呼吸暂停低通气指数(apneahypopneaindex,AHI)呈负相关(P﹤0.01),与最低血氧饱和度(MinSaO2)呈正相关(P﹤0.05);③OSAHS患者术后口咽局部截面积与无鼾者间无统计学差异(P>0.05);④手术后口咽局部截面积的改变值与PSG指标改善值之间无相关性(P>0.05)。结论口咽局部截面积可以作为病情轻重的推测指标及UPPP的指导指标,但术后的变化值不能作为手术疗效的预测指标。更多还原

【Abstract】 OBJECTIVE To determine whether the secar of oropharynx in OSAHS patients have anything to do with PSG parameters, whether it may be adapted as an index of OSAHS severity and guideline of UPPP operation, and whether its change post-operation may serve as a predictive index of therapeutic effectiveness. METHODS The secar of oropharynx of 20 OSAHS patients and 20 control patients were obtained by electronic laryngeal endoscope and graphic processing. The PSG of these 20 OSAHS patients were detected both pre- and post-operation. RESULTS ①In contrast to the control patients,stenosis may be seen in the secar of oropharynx of OSAHS patients(P<0.01);②The secar is inversely correlated to AHI(P<0.01) and directly correlated to MinSaO2(P<0.05);③The secar of OSAHS patients after operation does not different significantly from that of control patients(P>0.05);④The change of secar and PSG parameters do not readily correlate(P>0.05). CONCLUSION The secar of oropharynx can be regarded as a predictive index for OSAHS severity and guideline for operation, but the change of secar after operation can not be used as a predicitive index for therapeutic effectiveness.更多还原