【摘要】 SPINDLY(SPY)作为一负调节子参与GA的信号转导,34肽重复结构(TPR)与C-端区域对其正常功能都十分重要。SPY基因在植物中呈组成型表达,其蛋白主要出现在细胞核部位。SPY蛋白与动物中的氧连N-乙酰葡萄糖胺转移酶(OGT)具有广泛的同源性,两者可能有着类似的作用机制。本文主要介绍GA突变体、SPY基因、SPY蛋白及其在大麦中的同源物HvSPY的结构与功能相关方面的一些研究进展。更多还原

【Abstract】 Many results have shown SPINDLY (SPY) is involved in gibberellic acid (GA) signaling as a negative regulator, the tetratricopeptide repeat domain and C-terminal region have important roles for its function. The SPY gene is expressed constitutively in plants, and most of the SPY protein presents in nucleus. The SPY protein has significant similarity to O-linked GlcNAc transferase (OGT) from animals, which suggests that it may also have OGT activity. In this review, we highlighted research progress GA mutants、function of SPY gene and SPY protein and the homologue in barley (HvSPY).更多还原