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劳损愈贴膜的研制及安全性实验

The creation of Laosun Yutie plaster and safety experiment

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【作者】 李沛李莉庄严郭会卿陈茜安丙辰

【Author】 LI Pei~(1), LI Li~(2), ZHUANG-Yan~(3), GUO Hui-qing~(4), CHEN Qian~(5),AN Bing-chen~(1)(1. Henan Province College of Traditional Chinese Medicine, Zhengzhou 450008, China; 2. Henan Province Tumour Hospital, Zhengzhou 450008, China; 3. Henan Province Xinxin Grug Groupe, Zhengzhou 450052, China; 4. Henan Province Traditional Chinese Medicine Hospital, Zhengzhou 450002, China;5. Henan Province Medical Science Graduate School, Zhengzhou 450052, China)

【机构】 河南中医学院河南省肿瘤医院河南省信心药业集团河南省中医院河南省医学科学研究所河南中医学院 河南郑州450008河南郑州450008河南郑州450052河南郑州450006河南郑州450008

【摘要】 目的:制备一种治疗腰肌劳损症的纯中药贴膜剂———劳损愈贴膜。方法:经蒸馏、提取、浓缩、干燥等现代特殊工艺将当归、红花、乳香、没药、川芎、丁香、白芷等原料药制成干粉贴,并将蒸馏提取的挥发油及冰片加入乙醇溶液制成稀释液,两者合装制成贴膜剂,并做安全性试验。结果:家兔皮肤安全性试验证明该膏药无急性毒性、刺激性和过敏性。结论:本贴剂是安全、使用方便的新型外用药。

【Abstract】 Objective: To create an externally-applied TCD plaster(Laosun Yutie plaster) for the lumbar muscle strain (LMS). Method: ①The raw material such as angelica, safflower, frankincense, myrrh, clove and so on were turned into solid TCD plaster by a serial of modern treatment technology-distillation, extraction, condense, dehydration. Meanwhile, the naphtha from the distillation process and borneol were dissolved into ethanol solution and the dilution was thus made; ②The solid TCD plaster and the dilution from the aboved-mentioned process were put together to form the TCD plaster and the corresponding safety experiments were applied to rabits’skin. Result: The experimental results showed that it is neither of urgent toxicity, stimulary function, nor of allergy-inducing response. Conclusion: The laosun Yutie plaster was a newly externally-applied TCD plaster which could be used safely and handily.

【基金】 河南省科技攻关项目(0324420017)
  • 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,2005年09期
  • 【分类号】TQ461
  • 【被引频次】8
  • 【下载频次】252
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