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复方甘草酸苷联合地氯雷他定治疗慢性荨麻疹的疗效观察
Observation of Curative Effects of Compound Glycyrrhizin Combining Desloratadine in the Treatment of Chronic Urticaria
【摘要】 目的:观察复方甘草酸苷联合地氯雷他定治疗慢性荨麻疹的疗效。方法:将103例慢性荨麻疹患者随机分为治疗组和对照组,治疗组给予复方甘草酸苷联合地氯雷他定治疗,对照组单独应用地氯雷他定治疗,疗程均为2wk。结果:治疗组与对照组的总有效率分别为96.15%、82.35%,2组间有显著性差异(P<0.025)。复方甘草酸苷不良反应极少且轻微,联合用药未增加或加重不良反应。结论:复方甘草酸苷联合地氯雷他定治疗慢性荨麻疹疗效显著,不良反应少。
【Abstract】 OBJECTIVE:To observe the clinical efficacy of compound glycyrrhizin combining desloratadine in the treatˉment of chronic urticaria.METHODS:103patients with chronic urticaria were randomly divided into treatment group which were treated with compound glycyrrhizin plus desloratadine and controlled group which were treated with single desloratadine.The courses of treatment for both groups were2weeks.RESULTS:The total effective rates of the treatment group and the controlled group were96.15%and82.35%,respectively.There were significant differences between the2groups(P<0.025). Little and light ADR was found in compound glycyrrhizin and no exacerbation was found in the drug combination of compound glycyrrhizin plus desloratadine.CONSLUSION:It is of significant curative effects and little ADR to use compound glycyrrhizin combining desloratadine in the treatment of chronic urticaria.
【Key words】 Compound glycyrrhizin; Desloratadine; Chronic urticaria; Curative effects;
- 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2005年15期
- 【分类号】R758.24
- 【被引频次】14
- 【下载频次】136