【摘要】 目的 :比较2型糖尿病4种治疗方案的成本 -效果。方法 :运用药物经济学成本 -效果分析方法 ,对4种治疗方案 (A组 :阿卡波糖 ;B组 :格列齐特 +二甲双胍 ;C组 :胰岛素 ;D组 :瑞格列奈 +二甲双胍 )进行评价。结果 :4组空腹血糖控制效果具有显著性差异 (P<0.05) ,而空腹血浆胰岛素、β 细胞功能指数、胰岛素敏感指数均无显著性差异 (P>0.05)。结论 :4种治疗方案都能将血糖控制在理想范围 ,但从机体对胰岛素的敏感性和 β 细胞功能及总有效率方面考虑 ,则以瑞格列奈 +二甲双胍方案为最好。更多还原

【Abstract】 OBJECTIVE:To compare the economical effects of four treatment schemes on type2diabetes.METHODS:Four treatment schemes(Group A:Acarbose;Group B:Gliclazide+Metformin;Group C:Insulin;Group D:Repaglinide+Metˉformin)of type2diabetes were compared by a cost-effect analysis method in pharmacoeconomics.RESULTS:After treatment for3months,fasting blood glucose level of four schemes were of significant differences(P<0.05),while there were no sigˉnificant difference in the in fasting plasma insulin,βcells function and insulin sensitivity(P>0.05).CONCLUSION:Blood sug_ ar level can be controlled to an ideal level through the four treatment schemes;while Group D is better considering the sensiˉtivity of organism to insulin,the function ofβcell and the overall efficiency.更多还原