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妇科恶性肿瘤患者甲状旁腺激素相关蛋白与高血钙的相关性研究
Study of the association between hypercalcemia and parathyraid hormao-related protein in gynecologic malignancy
【摘要】 目的:探讨妇科恶性肿瘤患者高血钙与甲状旁腺激素相关蛋白(PTHrP)的相关性。方法:对宫颈癌6例、卵巢癌4例(透明细胞癌3例、卵巢甲状腺肿1例)所致高血钙患者术前进行PTHrP放射免疫测定。结果:血钙与PTHrP呈正相关(Y=2.433 9+0.455X),其相关系数r=0.903,对r进行假设检验,P<0.000 1。结论:PTHrP是妇科恶性肿瘤引起高血钙的主要体液因子之一。
【Abstract】 Objective:To study the relationship between humoral hypercalcemia and parathyroid hormone-related protein(PTHrP) in gynecologic malignancy.Methods:Serum calcemia and PTHrP were detected by radio immunoassay in 10 patients with gynecologic malignancy(cervical carcinoma 6;ovarian clear cell carcinoma 3;strumal carcinoid of ovary 1).Results:It was positive correlation between serum calcemia and PTHrP(Y=2.4339+0.455X).γ=0.903,P<0.0001.Conclusion:PTHrP was one of main factors caused HHM.
- 【文献出处】 中国妇幼保健 ,Maternal and Child Health Care of China , 编辑部邮箱 ,2005年19期
- 【分类号】R737.3;
- 【被引频次】5
- 【下载频次】108