【摘要】 目的:建立学龄前期儿童超声骨密度正常参考值。方法: 选择出生~72月龄深圳出生和/或居住的正常儿童566例为检测对象。0~12月龄(包括整12月龄) 每月一组; >12月龄(1岁) ≤36个月龄(3岁) 以3个月为一组; >36月龄(3岁) ≤72月龄(6岁) 以6月为一组, 共26组。用定量超声骨密度仪(QUS) 测定受检者足跟部骨密度(BMD) 值, 同时测量受检者的身高(cm)、体重(kg)。结果: 出生~72月龄正常儿童BMD正常参考值(g/cm2 ): 0 ~1月: 0 .570±0 .074;1~2月: 0. 549±0. 070; 2~3月: 0 .423±0 .074; 3~4月: 0 .456±0 .093; 4~5月: 0. 454±0 .109; 5~6月: 0. 392±0 .061; 6~7月: 0 .437±0 .051; 7~8月: 0 .455±0.073; 8~9月: 0 .475±0 .070; 9~10月: 0 .474±0 .077; 10~11月: 0 .481±0 .056;11~12月: 0 .487±0 .035; 12~15月: 0 .504±0 .076; 15~18月: 0 .499±0 .114; 18~21月: 0 .591±0 .165; 30~33月: 0 .517±0. 135; 33~36月: 0 .500±0 .176; 36~42月: 0 .439±0 .117; 42~48月: 0 .473±0 .172; 48~54月: 0 .445±0 .102; 54 ~60月: 0. 431±0 .108; 60~66月: 0 .447±0. 077; 66~72月: 0 .439±0 .092。结论: 0 ~72月龄男、女童之间BMD无差异(P>0. 05)?更多还原

【Abstract】 Objective:To set up normal reference value of bone mineral density (BMD) in healthy preschool children.Methods:566 healthy children aged 0~72 months born/lived in Shenzhen selected as subjects divided into 26 groups: each month from 0~12 months as one group; every 3 months from 12 to 36 months as one group; every 6 months from 36 to 72 months as one group. The calcaneus BMD values were determined by QUS, and height and weight of subjects were measured.Results:The normal reference value (g/cm 2) of BMD in healthy children aged 0~72 months were 0.570±0.074 from 0 to 1 month, 0.549±0.070 from 1 to 2 month, 0.423±0.074 from 2 to 3 month, 0.456±0.093 from 3 to 4 month, 0.454±0.109 from 4 to 5 month, 0.392±0.061 from 5 to 6 month, 0.437±0.051 from 6 to 7 month, 0.455±0.073 from 7 to 8 month, 0.475±0.070 from 8 to 9 month, 0.474±0.077 from 9 to 10 month, 0.481±0.056 from 10 to 11 month, 0.487±0.035 from 11 to 12 month, 0.504±0.076 from 12 to 15 month, 0.499±0.114 from 15 to 18 month, 0.591±0.165 from 18 to 21 month, 0.517±0.135 from 30 to 33 month, 0.500±0.176 from 33 to 36 month, 0.439±0.117 from 36 to 42 month, 0.473±0.172 from 42 to 48 month, 0.445±0.102 from 48 to 54 month, 0.431±0.108 from 54 to 60 month, 0.447±0.077 from 60 to 66 month and 0.439±0.092 from 66 to 72 month.Conclusion:There were no significant differences in BMD between male and female children from 0~72 months ( P >0.05). The changes of BMD should be related to rate of increases of height and have good correlation with weight ( P <0.05), which could be influenced by accumulation in fetus period, sports and rational nutrition.更多还原