【摘要】 目的建立止咳平喘胶囊(西洋参,杏仁,黄芩,甘草,川贝母等)质量标准。方法用薄层色谱法鉴别西洋参、甘草、川贝母;用高效液相色谱法测定人参皂苷Rb1含量,采用μBondpackC18柱,以乙腈水(34∶66)为流动相,流速1.2mL·min-1,检测波长203nm,柱温40.0℃,灵敏度0.02AUFS。结果人参皂苷Rb1含量在0.612～6.12μg呈良好的线性关系,平均回收率97.20%,RSD为2.25%。结论建立的定性定量方法简便、重复性好,可作为止咳胶囊的质量控制。更多还原

【Abstract】 AIM: To establish the quality standard for Zhike Pingchuan Capsule （Radix Panacis Quinquefolii, Semen Pruni Armeniacae, Radix Scutellariae, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, etc.）. METHODS: Radix Panacis Quinquefolii, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae in Zhike Pingchuan Capsule were identified by TLC and ginsenoside Rb₁ was determined by HPLC. The analysis was carried out on C_<sup>18 column by HPLC. The mobile phase was CH₃CN-H₂O（34∶66）. The flow rate was 1.2 mL·min^-1 and the detection wavelength was at 203 nm. The column temperature was at 40.0 ℃ and sensitivity was 0.02 AUFS. RESULTS:The average recovery was 97.20% and RSD was 2.25% and the linear range of ginsenoside Rb₁ was in 0.612-⁶.120 μg. CONCLUSION:This method is simple, rapid with a good reproducibility. This method can be used for the quality control of Zhike Pingchuan Capsule.更多还原