【摘要】 目的:检测血清ECP含量并探讨其在支气管哮喘患者中的临床应用价值。方法:使用UniCAPl00型自动酶免疫荧光分析系统测定。结果:正常人ECP含量为(4.76±3.28)μg/L;38例支气管哮喘患者急性发作期:治疗前ECP含量为(23.75±32.50)μg/L,治疗后ECP含量为(8.36±5.27)μg/L,41例缓解期支气管哮喘患者ECP含量为(10.98±4.24)μg/L。哮喘患者急性发作期,缓解期血清ECP水平均高于正常人,统计学差异有显著性(P<0.01)。结论:血清ECP水平反映气道的炎症程度,并可作为哮喘的诊断,疗效监测和预后判断指标。更多还原

【Abstract】 Objective To determine the serum ECP level and evaluate its clinical application in the asthma patients.Methods The serum ECP concentrations were measured by UniCAP automatic enzyme-fluoroimmunoassay system.Results The serum ECP concentrations of normal subjects was(4.76±3.28)μg/L of 38 asthmatic patients with acute asthma before the treatment was(23.75±32.50)μg/L;And after the treatments was(8.36±5.27)μg/L;The serum ECP concentrations of 41 asthmatic patients in remission was(10.98±4.24)μg/L.The serum level of ECP in the patients with acute asthma and in remission were higher than that of normal subjects.And it showed difference(P<0.01).Conclusion The serum ECP level reflects airway inflammatory status and helps predict the exacerbation and severity of asthma.It might be a useful marker in diagnosis of asthma and in monitoring the efficacy Of anti-inflammatory treatment in asthma.更多还原