【摘要】 目的:观察异丙酚靶控输注(TCI)用于心内直视手术麻醉诱导时的血流动力学及心率变异性(HRV)变化。方法:28例心脏病患者随机分为A、B两组,A组采用Diprifu-sor/TCI系统分步诱导给药,B组人工推注异丙酚,观察HR、BP、SpO2、ECG、HRV诱导前(T0)、意识消失时(T1)、插管时(T2)、插管后1min(T3)、3min(T4)、5min(T5)变化。结果:A组各时点HR、SpO2、DBP与T0相比无明显变化(P>0.05),HRV、SDP各时点明显低于T0(P<0.05),但插管后无明显异常;B组T1、T2的HR、BP明显低于T0、T3、T4、T5,也明显低于A组各时点(P<0.05),T3的TP、HF明显低于T0和A组(P<0.05)。结论:异丙酚TCI分步诱导可以安全地用于心内直视手术的麻醉诱导。更多还原

【Abstract】 Objective: To observe the hemodynamics and HRV caused by TCI during the induction period of the intracardiac surgery. Methods:28 cases of cardiopathy were chosen and divided into 2 groups as A and B which accepted propfool infusion by Diprifusor/TCI system or by manual respectively. The HR、Bp、SpO₂、ECG and HRV were observed 6 times on T₀（pre-induction）, T₁（unconsciousness）,T₂（intubating）,T₃（1min after intubating）,T₄（3mins after intubating） and T₅（5mins after intubating）.Results: Hardly any change of the HR,Spo₂ and DBp occurred in the group A compared with those indexes of T₀ while the HRV and SBP decreased on T1 and T₂ as compared with T₀（P<0.05）. All the indexes observed in group A on T₃,T₄ and T₅ became normal as T₀ without obvious difference. The HR and Bp of group B on T₁ and T₂ became obviously lower than those on T₀,T₃,T₄ and T₅,and lower than those indexes of group A（P<0.05）. Conclusion:The target controlled infusion （TCI） of propfol can be used in anesthesia induction of the intracardiac surgery safely.更多还原