【摘要】 目的了解葡萄球菌属对常用抗生素的耐药情况,为临床用药提供依据。方法采用Kirby-Bauer琼脂扩散药敏试验法检测所分离的1002株葡萄球菌对15种常用药物的耐药率。结果1002株葡萄球菌中金黄色葡萄球菌589株,凝固酶阴性葡萄球菌413株。药敏试验结果中未发现耐万古霉素的葡萄球菌,呋喃妥因、阿米卡星对葡萄球菌有较好的抗菌活性;葡萄球菌对β-内酰胺类抗生素(包括青霉素类、头孢菌素类、碳青酶烯类抗生素)普遍耐药。结论葡萄球菌对常用抗菌药物呈高耐药率,且有逐年增高的趋势,医院应重视细菌耐药性监测,合理使用和控制滥用抗生素。更多还原

【Abstract】 Objective To study the relationship between drug resistance of Staphylococcus and the antibiotics and to provide the reference for the clinical therapy. Methods To collect data of the 1002 stratus of Staphylococcus , and make analysis on the drug resistance of the common medicines. The test was performed on strains using standard Kirby - Bauer method. Results A total of 1002 Staphylococcus were isolated, among the 589 strains were Staphylococcus aureus and the strains of coagulase negative staphylo-coccus(CNS) were 413. None of drug resistance of Staphylococcus in Vancomycin were found, Nitrofurantoin and Amikacin have a good antibacterial on Staphylococcus , it has a common drug resistance in penicillins, cephalosprism and carbapenenms. Conclusion The drug resistance rata of Staphylococcus is high and the tendency is getting higher . Attaching importance to monitor the drug resistance of bacterium and reasonable application and control abuse of antibiotics in clinic.更多还原