节点文献
江门市人群HBV感染模式与HCV感染情况
Survey of infectious model of hepatitis B virus and the infectious statu s of hepatitis C virus in population of Jiangmen City
【摘要】 目的 为了解江门市人群乙型肝炎病毒(HBV)感染模式与丙型肝炎病毒(HCV)双重感染情况,进行血清病原学检测。 方法 选取774例HBV感染阳性血清,同时用ELISA方法作抗-HCV检测。 结果 对1998年7月~2003年12月间体检中检出的774例标志物阳性血清归类分析,发现有18种HBV感染模式,其中以HBsAg、HBeAb、HB cAb和HBsAg、HBeAg、HBcAb为多见,阳性构成比分别为42. 38%和29. 97%。在HBV感染者中HCV感染的检出率为11. 63%。不同HBV感染模式组别的抗-HCV阳性率差异有显著性意义(χ2=24 .38, P <0 .001)。 结论 既往感染过HBV,不仅没有交叉免疫力,而且重叠感染HCV的危险性增加,应引起高度重视。
【Abstract】 Objective To explore the pattern of HBV markers and distribution of coinfected with HBV and HCV among population. Methods Sera from 774 cases with positive HBV markers were de tected of HCV by ELISA. Results The results showed that 18 patterns were found.The p a ttern of positive HBsAg,HBeAb,HBcAb,(42.38)and the pattern of positive HBsAg,HB c ag,HBcAb(29.97%) were more often seen.The difference of the positive rate of a nt i-HCV among various patterns of HBV markers was significant(χ~2=24.38,P< 0.001). Conclusion Special attention be paid to the increase of risk of coinfection with HCV in patients previous infectied with HBV and without cro ss immunity.
【Key words】 Hepatitis B virus; Hepatitis C virus; Pattern of infected mark;
- 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2005年02期
- 【分类号】R512.62
- 【被引频次】3
- 【下载频次】25