抗血小板药物中断对缺血性中风的影响

【摘要】 目的：研究APD中断对中风的影响。方法：在连续的住院患者中，调查APD中断后缺血性中风患者APD中断的原因，中风的机制以及中风发作的潜伏期。结果：在289例缺血性中风患者中，4．49％有APD中断，ADP中断与中风起病的潜伏期为7．4±1．26天。结论：部分缺血性中风的发病与ADP中断有关。在带有多种血管病危险因子的人群中，ADP中断是缺血性中风的一个高危因素。更多还原

【Abstract】 Objective: To study APD discontinuation’s influence on stroke. Methods: The authors studied the frequency of stroke occurring after APD discontinuation, the cause of discontinuation, and the delay between APD disruption and stroke. Results: in 289 cases of ischemic cerebrovascular diseases, 4.49% of strokes were related to a recent APD discontinuation, but all cases occurred between 6 and 10 days after drug discontinuation. Conclusions: the part of ischemic cerebrovascular disease cases is associated with APD discontinuation, the delay between APD disruption and stroke ADP is 7.4±1.26 days. This temporal pattern has biologic plausibility because the inhibited platelets circulate in the blood for about 10 days.更多还原