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青银注射液中总绿原酸的紫外含量测定

DETERMINATION OF THE CONTENT OF TOTAL CHLOROGENIC ACID IN QING YING INJECTION BY ULTRAVIOLET SPECTROPHOTOMETRY

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【作者】 何兵王琳田吉冯文宇邱华荣

【Author】 He Bing, et al Institute of Materia Medical, Luzhou Medical College

【机构】 泸州医学院药学院药研所泸州医学院药学教研室泸州医学院药学院药研所 四川泸州646000四川泸州646000

【摘要】 目的测定青银注射液中总绿原酸的含量。方法采用紫外分光光度法在324nm处测定吸收度,并用绿原酸的吸收系数计算其含量。结果青银注射液中总绿原酸的平均含量为19.38mg/ml。结论该法操作简便快速,稳定性,精密度,重现性和回收率均较好,可用于青银注射液生产过程中的质量控制。

【Abstract】 Objective: To determine the content of total chlorogenic acid in Qingying injection. Methods: Ultraviolet spectrophotometry was employed to determine the absorbance at wavelength 324nm. Then the content was calculated by absorption coefficient of chlorogenic acid. Results: The average content of total chlorogenic acid is 19.38 mg/ml. Conclusion: This method is simple, rapid, and stable, with good precision,reproducibility, and recovery. It can be used for quality control in production process of Qingying injection.

【基金】 “九五”国家科技攻关项目(96-901-05-020)
  • 【文献出处】 泸州医学院学报 ,Journal of Luzhou Medical College , 编辑部邮箱 ,2005年06期
  • 【分类号】R286.0
  • 【被引频次】5
  • 【下载频次】255
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