【摘要】 目的研究蜂胶醇的提物对线粒体氧自由基损伤的保护作用。方法采用FeSO4/半胱氨酸(Fe2+/Cys)体系造成鼠肝脏线粒体损伤模型,测定线粒体肿胀、丙二醛(MDA)、琥珀酸脱氢酶(SDH)。结果Fe2+/Cys损失组与正常对照组比较,线粒体肿胀度和MDA均明显增加,SDH活力明显降低。结论蜂胶醇提物可剂量依赖性保护大鼠肝脏线粒体的氧自由基损伤。更多还原

【Abstract】 Objective To study the protection function of Ethaol exaction from ropolis to damage of the rat liver from oxygen free radicals.Methods We adopt the model that the Fe²⁺/Cys system results in the damage of the rat liver from the oxygen free the adicals,the degree swells of mitochondrion,controlled with the content of MDA,activity of SDH were measured respectively. Results Fe²⁺/Cys damage group compared with normal control,the swells degree and MDA of mitochondrion increased obviously,the vitality of SDH decreased obviously. Conclusions The exaction from propolis could protect mitochondrion on Fe²⁺/Cys damage.更多还原