【摘要】 幽门螺杆菌是人类最常见的致病菌之一,与慢性胃炎、消化性溃疡、肠上皮化生、胃癌、粘膜相关性淋巴样组织(MALT)淋巴瘤等密切相关.幽门螺杆菌呈螺旋形,有鞭毛,有多种基因亚型,在世界人口中感染率达50%,在慢性胃炎和消化性溃疡患者中感染率更高.幽门螺杆菌的主要传染源是人类,可通过口-口途径、粪-口途径、医源性途径传播.幽门螺杆菌的致病因素包括毒力因子、细胞因子、免疫学因子、机体的遗传易感性等.认清幽门螺杆菌的传播过程和致病机理对于幽门螺杆菌的防治有着非常重要的意义.更多还原

【Abstract】 Helicobacter pylori(H.pylori) is one of the most common pathogens which is closely associated with chronic gastritis,peptic ulcers,intestinal epithelium metaplasia,gastric carcinoma and MALT.H.pylori takes the form of spiral.It has flagellae and many gene isoforms.The infectious rate of it in the global population has reached 50% and is more in the patients with chronic gastritis or peptic ulcers.The main source of infection of H.pylori is mankind.H.pylori can be spread through the way of mouth to mouth,stool to mouth and medicine.The etiological factors of H.pylori include virulence factors,cellular factors,immunological factors,heredity susceptibilities of bodies.To recognize the propagation process and pathogenic mechanism of the H.pylori has a vital significance in the prevention and therapy of it.更多还原