【摘要】 生长抑素(SS)是一种抑制脑垂体分泌生长激素的神经调节肽,广泛分布于脊椎动物中枢和外周神经系统,胰腺和胃肠道等组织的一类结构相关肽,以14 肽为主,包括28肽、12肽及SS原等多种形式。SS的多种生物学功能是通过与G蛋白偶合的5 种不同亚型的生长抑素受体(SSTR)而实现的。5 种不同亚型SSTR主要分布于脑、胰腺、垂体等多种组织中,其各自的功能也有一定差异。文章就SS及其受体在体内分布、生理功能、应用方面的研究进展和发展前景做一综述。更多还原

【Abstract】 Somatostatin is a kind of brain-gut peptide that has a wide distribution not only in neural and gastrointestinal system but also in lymphoid organs and so on .It mainly includs SS-14 and SS-28,SS-12. All kinds of function of somatostatin by G-protein unite 5 kinds of different somatostatin receptors realities. Five kinds of different somatostatin receprors mainly distribution in brain and pancreas organs and so on. But each kind of recepror function has some differences.The article mainly reviewed distribution、physical function and application of somatostatin and its receptor,and introducea its progress of research in the future.更多还原