【摘要】 美味猕猴桃 (AcitinidiadeliciosaC .F .liangetA .R .Ferguson)为猕猴桃科猕猴桃植物。目的 :观察美味猕猴桃根提取物对肿瘤细胞的抑制和凋亡影响。方法 :采用MTT法、集落形成法、生长曲线法和Hoechst 3 3 2 5 8荧光染色法测定美味猕猴桃根提取物对白血病细胞株L12 10和P3 88D1、宫颈癌细胞株Hela、人胃癌细胞株SGC790 1、黑色素瘤细胞株B16、神经性肿瘤细胞株NG10 8-15的生长抑制和凋亡影响。结果 :美味猕猴桃根提取物均可抑制 6种肿瘤细胞株的增殖 ,并可导致部分细胞凋亡和死亡。结论 :美味猕猴桃根提取物在体外具有抗肿瘤作用更多还原

【Abstract】 Objective: To observe the effects of extracts from roots of Acitinidia delicilsa on the growth inhibition and apoptosis in carcinoma cell lines. Methods: The growth inhibition and apoptosis was analyzed by MTT, Hoechst 33258 fluorescence, Cell colony and cell growth curve measurement chnique in the stomach carcinoma SGC7901, Lymphocytic leukemia L1210, Lymphoid neoplasm P388D1, Tumor of cervix uteri HeLa, Melanoma B16 and mouse neuroblastoma x rat glioma hybrid NG108-15 cells lines. Results: The growth inhibition and apoptosis is induced by extracts from roots Acitinidia delicilsa in all cell lines. Conclusion: The results shown that extracts from roots Acitinidia delicilsa possesses the role of antitumors in cell culture.更多还原