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山羊传染性胸膜肺炎支原体和绵羊肺炎支原体对抗菌药物敏感性的研究
Sensitivity of Mycoplasma ovipneunoniae Y-98 strain and Mycoplasma mycoides subsp. mycoides Y-goat strain to eight antibacterial drugs in vitro
【摘要】 测定了环丙沙星、氧氟沙星、单诺沙星、红霉素、罗红霉素、泰乐菌素、泰妙菌素、四环素等8种药物对羊肺炎支原体两个标准株Y 98和Y goat的体外抑菌浓度以及红霉素与氧氟沙星、泰乐菌素对Y goat和四环素与氧氟沙星、泰乐菌素对Y 98的联合药敏作用。结果表明,这8种抗菌药物对Y goat和Y 98的MIC(μg/mL)分别为:环丙沙星0.223、0.00223,氧氟沙星0.281、0.0140,单诺沙星0.136、0.0140,红霉素0.0218、无效,罗红霉素0.0327、无效,泰乐菌素0.0422、0.0390,泰妙菌素0.0217、0.0520,四环素0.195、0.0520。红霉素与氧氟沙星的联合药敏指数为1,是相加作用;红霉素与泰乐菌素对Y goat的联合药敏指数为1.5,是无关作用;四环素与氧氟沙星、泰乐菌素对Y 98的联合药敏试验指数均为0.375,是协同作用。
【Abstract】 The effects of 8 kinds of antibacterial drugs on MO Y-98 and M.myc.sub.Myc. Y-goat in vitro were (reported). Their minimal inhibitory concentrations(MIC, μg/mL) were 0.223 and 0.002 23 with ciprofloxacin, (0.281) and 0.140 with ofloxacin, 0.136 and 0.014 0 with danfloxacin, 0.021 8 and invalid with eromycin, (0.032 7) and invalid with roxihromycin, 0.044 2 and 0.039 0 with tylosin, 0.021 7 and 0.052 0 with taimulin, 0.195 and 0.052 0 with tetracycline, respectively. The fractional inhibitory concentration(FIC) index of (eromycin) with ofloxacin and tylosin on Y-goat strain were 1 and 1.5 respectively. The FIC index of tetracycline with ofloxacin or tylosin on Y-goat was 0.375.
【Key words】 antibiotics; Mycoplasma pneumoniae of sheep and goat; MIC; fractional inhibitory concentration ((FIC)index);
- 【文献出处】 中国兽药杂志 ,Chinese Journal of Veterinary Drug , 编辑部邮箱 ,2004年05期
- 【分类号】S858.27
- 【被引频次】14
- 【下载频次】213