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顺德容奇地区肺癌危险因素的病例对照研究

Case-control Study for Risk Factors of Lung Cancer in Rongqi Area

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【作者】 卢家强陈亚利霍敏琴

【Author】 LU Jia-qiang,CHENG Ya-li,HUO Min-qin.Rongqi Hospital,Shunde District,Foshan City,Guangdong Province 528303,China

【机构】 广东省佛山市顺德容奇医院广东省佛山市顺德容奇医院 528303528303528303

【摘要】 目的 探讨顺德容奇地区肺癌的危险因素。方法 采用病例对照研究方法 ,对 12 0例肺癌患者及 12 0名非肺癌者 (无肿瘤史 )采用统一的标准问卷调查 ,对数据资料进行统计学分析 ,计算各危险因素的OR值及P值。结果 吸烟 (OR =5 67) (尤其是吸烟指数≥ 40 0支·年 ,OR =11 8) ;住在大气污染区 (OR =3 0 1) ,室内污染严重 (OR =2 94) ,长期接触油烟 (OR =2 2 ) ,室内长期烧香 (OR =3 45 ) ,与容奇地区的肺癌显著相关 ;被动吸烟 (OR =0 91) ,经常吃蔬菜水果 (OR =0 81) ,与肺癌无显著相关 ,经常体育锻炼 (OR =0 5 7) ,与肺癌负相关有显著性。结论 吸烟、大气污染、室内污染、长期精神压抑、既往呼吸疾病史、家族肿瘤史是容奇地区肺癌主要危险因素 ,体育锻炼是保护因素 ,被动吸烟、饮食作用有待进一步研究。

【Abstract】 Objective To investigate the risk factors of lung cancer in Rongqi area Shunde,Foshan City. Methods A case-control study was carried out.Both 120 cases with lung cancer and 120 cases without lung cancer(more exactly no tumor before)were required to answer the standard questionnaire.All OR values and P values of risk factors were obtained statistically,based on the descriptive analysis of the survey. Results Smoking( OR =5.67)?heavy smoking(smoking index≥400 piece.year)( OR =11.8)?living in air-polluted area( OR =3.01)?indoor pollution( OR =2.94)?long-term contact with oil mist( OR =2.2)?long-term indoor burning joss sticks( OR =3.45)were significantly related to local lung cancer,while passive smoking( OR =0.91)?adequate intake of fresh vegetable and fruit( OR =0.81)with no significant relation.Regular exercises( OR =0.57)had a significantly negative relation to local lung cancer. Conclusions The risk factors of lung cancer in Rongqi district mainly include smoking,pollution,indoor pollution,long-term depression,positive chronic pulmonary diseases,family history of cancer.Physical exercise is one of the protective factors,but the role of passive smoking and dietary needs further study.

【关键词】 肺肿瘤危险因素病例对照研究
【Key words】 Lung neoplasmsRisk factorCase control study
【基金】 广东省医学技术立项科研课题
  • 【文献出处】 中国自然医学杂志 ,Chinese Journal of Natural Medicine , 编辑部邮箱 ,2004年01期
  • 【分类号】R734.2
  • 【被引频次】5
  • 【下载频次】155
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