【摘要】 纳米粒以其独特的纳米功效 ,在新型药物制剂研究中受到很大重视。近年来的一些研究表明纳米粒子在药物经皮及黏膜给药中也有着独特作用 ,尽管机理还不清楚 ,但为经皮及黏膜给药提供了新的发展方向。作者主要综述了纳米粒子应用到经皮及黏膜给药体系的一些最新研究进展 ,主要包括脂质体纳米粒 ,天然高分子及合成高分子纳米粒的经皮及黏膜给药系统的研究成果更多还原

【Abstract】 Nanoparticles had received much attention in the development of new kind of pharmaceutical formation because of the special nano-effectivity. Recen t ly, some studies discovered the special functions of the nanoparticles in transd ermal and transmucosal drug delivery systems. Even though the acting mechanism o f the nanoparticles in these drug delivery systems are not known, these discover ies of the special function of the nanoparticles provide new developing prospect to the drug delivery systems. This paper mainly reviews the present studying re sults about the nanoparticles used in the transdermal and transmucosal drug deli very systems, including the lipid nanopaticles, natural polymer and the synthesi zed polymer nanoparticles.更多还原