【摘要】 目的　探讨宫颈疾病专科门诊宫颈疾病发病情况及特点,为宫颈癌早期预防工作提供依据。方法　对2000年7月至2002年6月在深圳市妇幼保健院宫颈疾病专科门诊就诊的1686例病人的临床资料进行回顾性分析,并对相关危险因素进行多元回归分析。结果　宫颈炎性病变占88 14%,宫颈上皮内瘤样病变(ＣＩＮ)占8 19%,宫颈癌占1 36%。宫颈良性病变中人乳头瘤病毒(ＨＰＶ)阳性率为22 36%;宫颈癌及癌前病变者中ＨＰＶ阳性率为64 49%,明显高于宫颈良性病变组(Ｐ<0 01)。ＨＰＶ阳性者中ＨＰＶ亚临床感染及ＨＰＶ相关肿瘤感染占82 25%。宫颈癌及癌前病变高峰年龄段为36～45岁,回归分析显示ＨＰＶ感染、多性伴、性传播疾病病史是其发病的高危因素。结论　积极、谨慎对待宫颈炎性病变,ＨＰＶ阳性者进行严格的宫颈癌筛查是临床工作的重点;36～45岁年龄段应是城市医院宫颈癌防治的重点人群;社会因素对宫颈癌防治有一定的影响。更多还原

【Abstract】 Objective To investigate the incidence and characteristics of cervical pre-carcinoma and cervical carcinoma in cervical carcinoma screening outpatient department in hospital,and to provide evidence for taking measures against cervical carcinoma.Methods 1686 cases were enclosed in this study.The disease clinical distribution,HPV infection and age tendency were analysed by retrospective study.And the relative risk factor were analysed by logistic analysis.Results (1)In all cases,88 14% were cervicitis,8 19% were CIN,and 1 36% cervical carcinoma.(2)HPV positive rate was 22 36% in cervical benign diseases.In CIN and cervical carcinoma,HPV positive rate was 64 49%,significantly higher than that in benign disease(P<0 001).In HPV positive patients,82 25% was subclinic papilloxnam and HPV-related tumor.(3)The peak age of CIN and cervical carcinoma was 36～45 years.The logistic analysis showed that the risk factor were HPV infection,multiple sexual partners and STD history.Conclusion The cervicitis must be treated actively and carefully.The emphasis in cervical carcinoma screening should be put on HPV-positive patients.And the target populations are 36～45 years old.Social factor should be paid attention.更多还原