【摘要】 在磷霉素合成的过程中 ,涉及到以Pd/C为催化剂催化丙二烯磷酸部分加氢合成顺丙烯磷酸的一步反应。本实验以朗伯 -比耳定律为依据 ,通过配制一组不同丙二烯磷酸和顺丙烯磷酸含量的标准溶液 ,测得其特征吸收频率处的红外透过率 ,根据实验结果作二者关系的标准曲线。从而建立了一个相对简便实用、快速准确地同时分析丙二烯磷酸和顺丙烯磷酸的方法 ,进而应用于磷霉素合成反应中的Pd/C催化剂活性评价更多还原

【Abstract】 An infrared spectrometric method for the determination of1,2_propadienyl_phosphonic acid（1,2_PDPA）and cis_1propenyl phosphonic acid（cis_1PPA）in the synthetic process of phosphonoˉmycin was developed.A series of various concentrations of standard solutions of1,2_PDPA and cis₁ PPA were made_up and their IR transmittances were detected at the wavelengths of1629cm -1 ,1944cm -1 and1967cm -1 ,respectively.A linear relationship between their relative transmittances and the deˉgree of transformation of1,2_PDPA to cis_1PPA was obtained.The method could be used to determine the two compounds simultaneously.It could also be used to evaluate the activity of the Pd/C catalyst in the synthesis of phosphonomycin.更多还原